Nakanishi Lab
Laboratory of Molecular, Cellular and Developmental Biology
Principal Investigator: Nobuki Nakanishi, PhD
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Research Focus: Molecular, cellular and developmental biology
The Nakanishi lab has contributed to the identification of NR3A (GRIN3) subunits of the NMDA receptor family and their physiological and pathophysiological activities.
We have discovered the takusan gene family, which positively regulates synaptic structures and thereby protect synapses from pathological insults.
Specifically, we have generated various GRIN3 mouse mutants (knockout and overexpressor) and studied their phenotypes.