Scintillon Institute launches its first crowdfunding campaign! Did you know that 2.7 million Americans suffer from glaucoma and over 65% are women? Scintillon Institute believes the future of science begins today. But we need your help! We aim to purchase a confocal microscope for our newly established Eye Disease Research Center. Our goal is $500,000 by December 31. As a thank you, we are offering exciting perks, such as tickets to our 'Healthy Aging' lecture series and an exclusive lunch with our top scientists. To learn more and donate, please visit our campaign page. Thank you for sharing our vision!
Promising Finding to Combat Autism San Diego, CA A group of researchers at Scintillon Institute in San Diego, California demonstrated a promising therapeutic intervention for autism in an animal model. This study, published today in Nature Communications under the title of “NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism”, proposes a therapeutic strategy to mitigate the hallmarks of MEF2C haploinsufficiency syndrome (MCHS), a condition where patients who carry one copy of defective MEF2C gene suffer from severe neurological conditions including autism spectrum disorders, intellectual disabilities, and seizures. Neurons of normal versus mutant cells Continue reading
01 August 2017 FOR IMMEDIATE RELEASE Scintillon team to play key role in center for creating bioluminescent neuroscience tools San Diego, CA In a new collaboration, scientists will advance and freely circulate a research technology that makes brain cells able to produce, respond to, and communicate with light. Nathan Shaner, Ph.D. will lead Scintillon Institute’s contribution to a national center dedicated to developing and disseminating new tools based on bioluminescence. The five-year grant from the National Science Foundation aims to develop tools to give nervous system cells the ability to make and respond to light. Neuroscientists can use these tools to manipulate and observe the circuitry of the brain in a variety of model organisms. “NeuroNex Technology Hub” is a new collaboration of labs at Brown University, Central Michigan University and the Scintillon Institute. The team will improve upon and combine several unique bioengineering technologies to create new research capabilities, rooted in bioluminescence-the natural ability of cells to make light. They will then make their advances rapidly, easily, and freely available to the global scientific community. Shaner joins co-principal investigators Diane Lipscombe, Brown professor of neuroscience and director of the Brown Institute for Brain Science, and Ute Hochgeschwender, professor at CMU, on a team led by Christopher Moore, a professor of neuroscience at Brown. Justine Allen, a Brown neuroscience PhD alumna, will be the center’s administrative director. Creating a curriculum, which combines elements of biology, chemistry, physics and engineering, to engage and educate high school students will be a key facet of the center’s mission. “The highly visual nature of this research is a great way to get young people interested in science,” said Shaner. “Being able to see living neurons lighting up as they fire under a microscope can be a transformative experience for them.” Continue reading
The US Department of Defense Funds New Direction in Monitoring and Stimulating Neurons for Directly Interfacing with the Brain
Jun 8, 2017, San Diego: Scintillon Institute Associate Professor Nathan Shaner is part of a nine-laboratory team that has been awarded a contract from the Defense Advanced Research Projects Agency (DARPA) as part of President Obama’s BRAIN Initiative. This project, dubbed “IBIS: Implantable bioluminescence interface system for an all-optical neuroprosthesis to the visual cortex,” will be funded under DARPA’s Neural Engineering System Design (NESD) program. Ultimately, the IBIS team seeks to develop a neural interface system capable of simultaneously recording from more than one million neurons and stimulating more than one hundred thousand neurons in regions of the human sensory cortex. Accomplishing this goal will be a huge leap forward from existing neural interfaces, which are limited to much smaller numbers of neurons, and are too bulky and invasive to be used in human therapies. Continue reading
Tomorrow, March 3, 2017, Christopher K Glass, M.D., Ph.D., Professor of Cellular and Molecular Medicine, Professor of Medicine (UCSD) will present “Genome-wide approaches to defining microglia identity and function” at 1:15pm in the 6868 Nancy Ridge Drive seminar room. Continue reading
07 November 2016 For Immediate Release A new potential target for anti-aging discovered in protective protein San Diego, CA Research from the Scintillon Institute identifies a promising new target for future drug treatments for neurodegenerative disorders, including Alzheimer’s and Parkinson’s disease. Continue reading
Scintillon Institute proudly hosts Michael Karin, Ph.D. Distinguished Professor of Pharmacology, Ben and Wanda Hildyard Chair for Mitochondrial and Metabolic Diseases, American Cancer Society Research Professor (UCSD) “Positive and Negative Regulation of the NLRP3 Inflammasome Implications on Cancer, Aging and Neurodegeneration” on October 24th at 1pm Scintillon seminar room at 6868 Nancy Ridge Drive Continue reading
Scintillon Institute proudly hosts Alan S. Verkman, M.D. Ph.D. Director of the Cystic Fibrosis Research Development Program at University of California, San Francisco, former Established Investigator for the American Heart Association, and Senior Staff Member of the Cardiovascular Research Institute at University of California, San Francisco “Cystic fibrosis drug discovery and assay methods” Continue reading
Scintillon Institute congratulates A. Chakraborty and Z. Fullerton, the Grand Prize Winners of Scintillon Institute's STEM Art Contest! A. Chakraborty's dolphin had our team doing flips at the San Diego Festival of Science & Engineering EXPO day. Z. Fullerton's dragonfly created such a buzz at CSUSM's Super STEM Saturday that we just had to recreate it in the Shaner Lab's award winning Fluorescent Proteins.
On June 10th Scintillon Institute proudly hosts Charles F. Stevens, M.D. Ph.D. the Vincent J. Coates Professor at Salk Institute for Biological Studies, former investigator of the Howard Hughes Medical Institute, and member of US Academy of Sciences Continue reading