The Scintillon Institute's first publication, "Feeder-Free Derivation of Human Induced Pluripotent Stem Cells with Messenger RNA," by Jiwu Wang has been published in the new Nature family journal Scientific Reports.

The therapeutic promise of induced pluripotent stem cells (iPSCs) has spurred efforts to circumvent genome alteration when reprogramming somatic cells to pluripotency.  Our mRNA method uniquely affords unprecedented control over reprogramming factor (RF) expression while obviating a cleanup phase to purge residual traces of vector.