The Scintillion Institute’s Nathan Shaner and his collaborator Ute Hochgeschwender at Central Michigan University became recipients of a National Science Foundation (NSF) BRAIN EAGER grant for developing non-invasive optogenetics based on bioluminescence.

In 2013, The National Institute of Biological Imaging and Bioengineering (NIBIB) of National Institutes of Health (NIH) awarded more than $6.4 million for the continuation of the Bioengineering Research Partnership (BRP) Raman Flow Cytometry for Drug Discovery and Diagnostics.

This  multidisciplinary effort is led by Scintillon's Institute Professor John Nolan. The partnership aims to extend the multiparameter capabilities of flow cytometry by measuring Raman spectra from individual cells in flow. We are developing nanoparticle surface enhanced Raman scattering (SERS) tags, a new generation of spectral flow cytometers that can measure high resolution Raman spectra from individual cells, and software for Raman flow cytometry data analysis.

This project will take advantage of wild-type fluorescent proteins with novel optical properties to be cloned from a broad range of species, including several Great Barrier Reef corals made available through an international collaboration. 

We are extremely excited to welcome Professor Nolan to the Scintillon Team! Dr. Nolan is bringing his lab from the La Jolla Bioengineering Institute to join our Scintillon team.  His research focus on cytometry will add an exciting new dimension to the research possibilities at the Scintillon Institute.

Visit Nolan's Lab

The "A Bright Monomericgreen Fluorescentprotein Derived From Branchiostoma Lanceolatumpublication" was published in Nature Methods (10, 407-209, 2013)

We report a monomeric yellow-green fluorescent protein, mNeonGreen, derived from a tetrameric fluorescent protein from the cephalochordate Branchiostoma lanceolatum.